Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 17/20 | 0.62 |
| ▸ | CDK4 | P11802 | 13/20 | 0.62 |
| ▸ | CCND3 | P30281 | 13/20 | 0.62 |
| ▸ | CDK1 | P06493 | 12/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.62 |
| ▸ | CCND1 | P24385 | 10/20 | 0.61 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.58 |
| ▸ | CDK2 | P24941 | 5/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | CCNK | O75909 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541042 | 0.89 | CDK6 (0.60) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541020 | 0.88 | CCND1 (0.57) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541018 | 0.88 | CDK6 (0.68) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541013 | 0.85 | CDK4 (0.61) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541010 | 0.84 | CCND1 (0.58) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541021 | 0.82 | CDK6 (0.62) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL30541156 | 0.82 | CDK6 (0.60) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL24483440 | 0.81 | CDK6 (0.67) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL24482654 | 0.81 | CDK6 (0.68) | CDK6CDK4CCND3CDK1CCNA2 | |
| SCHEMBL29684256 | 0.81 | CDK6 (0.67) | CDK6CDK4CCND3CDK1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |