Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.64 |
| ▸ | PRKCI | P41743 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 4/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244213 | 1.00 | AGXT (0.64) | AGXTPRKCIKIF11PTPN5MGLL | |
| SCHEMBL30542012 | 0.89 | AGXT (0.52) | AGXTPRKCIKIF11PTPN5MGLL | |
| SCHEMBL10269541 | 0.87 | PRKCI (0.53) | AGXTPRKCIKIF11PTPN5RXRA | |
| SCHEMBL2652456 | 0.86 | AGXT (0.60) | AGXTPRKCIKIF11PTPN5MGLL | |
| SCHEMBL18297788 | 0.82 | PRKCI (0.76) | AGXTPRKCIACMSD | |
| SCHEMBL13761767 | 0.82 | PRKCI (0.56) | AGXTPRKCIKIF11PTPN5RXRA | |
| SCHEMBL27174499 | 0.82 | MAOB (0.64) | AGXTKIF11PTPN5RXRARXRB | |
| SCHEMBL30696290 | 0.82 | MAOB (0.64) | AGXTKIF11PTPN5RXRARXRB | |
| SCHEMBL894079 | 0.82 | AGXT (0.69) | AGXTKIF11PTPN5MGLLMAOB | |
| SCHEMBL3522621 | 0.82 | AGXT (0.64) | AGXTKIF11PTPN5MGLLMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757770-B | 3-Phenyl-4-hexynoic acid derivatives as GPR40 agonists | 赛隆制药股份公司 | 2023-10-03 | — | — | CN | disclosed |