Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542002 | 0.89 | AGXT (0.64) | AGXTPRKCIFFAR1ACMSDKIF11 | |
| SCHEMBL2244213 | 0.89 | AGXT (0.64) | AGXTPRKCIFFAR1ACMSDKIF11 | |
| SCHEMBL10269541 | 0.80 | PRKCI (0.53) | AGXTPRKCIACMSDKIF11PTPN5 | |
| SCHEMBL2652456 | 0.76 | AGXT (0.60) | AGXTPRKCIFFAR1ACMSDKIF11 | |
| SCHEMBL4191589 | 0.74 | PRKCI (0.72) | AGXTPRKCIACMSD | |
| SCHEMBL2257 | 0.73 | TAAR1 (0.60) | MGLLMAOB | |
| SCHEMBL30696290 | 0.72 | MAOB (0.64) | AGXTKIF11PTPN5S1PR1RXRA | |
| SCHEMBL894079 | 0.72 | AGXT (0.69) | AGXTKIF11PTPN5MGLLCASR | |
| SCHEMBL3522621 | 0.72 | AGXT (0.64) | AGXTFFAR1KIF11PTPN5MGLL | |
| SCHEMBL13761767 | 0.72 | PRKCI (0.56) | AGXTPRKCIACMSDKIF11PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757770-B | 3-Phenyl-4-hexynoic acid derivatives as GPR40 agonists | 赛隆制药股份公司 | 2023-10-03 | — | — | CN | disclosed |