Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613494 | 0.79 | MAPT (0.56) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL10662326 | 0.73 | MAPT (0.62) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL26613480 | 0.73 | MAPT (0.58) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL29746163 | 0.73 | MAPT (0.58) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL11125399 | 0.73 | NPC1 (0.50) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL3306566 | 0.72 | KIF11 (0.69) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL10664070 | 0.72 | MAPT (0.60) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| Bromide SCHEMBL11119640 | 0.71 | NPC1 (0.48) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| Bromide SCHEMBL11119646 | 0.71 | NPC1 (0.48) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL14865934 | 0.71 | KIF11 (0.68) | CYP11B1CYP11B2CYP2C9CYP2D6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403554-A | Therapeutic or prophylactic agent for amyotrophic lateral sclerosis | 东丽株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-116648245-A | Tetrahydroquinoline derivative and medical application thereof | 东丽株式会社 | 2023-08-25 | — | — | CN | disclosed |