Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056209 | 1.00 | PDE4B (0.51) | PDE4BPDE4DSLC22A12KDM4E | |
| SCHEMBL30542620 | 0.87 | PDE4B (0.46) | PDE4BPDE4DKDM4E | |
| SCHEMBL29056235 | 0.87 | PDE4B (0.46) | PDE4BPDE4DKDM4E | |
| SCHEMBL29056289 | 0.83 | SLC22A12 (0.41) | PDE4BPDE4DSLC22A12KDM4E | |
| SCHEMBL30542631 | 0.83 | SLC22A12 (0.41) | PDE4BPDE4DSLC22A12KDM4E | |
| SCHEMBL30542648 | 0.81 | PDE4B (0.50) | PDE4BPDE4DKDM4E | |
| SCHEMBL29056255 | 0.81 | PDE4B (0.50) | PDE4BPDE4DKDM4E | |
| SCHEMBL29056216 | 0.81 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL30542663 | 0.81 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL29056291 | 0.79 | ABCG2 (0.52) | SLC22A12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |