SCHEMBL30543005

SCHEMBL30543005

c1ccc(-c2ccc(-c3c4ccccc4cc4ccccc34)c3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
MAPT P10636 1/20 0.52
MPI P34949 1/20 0.52
GPR84 Q9NQS5 6/20 0.50
ALOX5 P09917 2/20 0.46
RECQL P46063 1/20 0.44
CES1 P23141 1/20 0.43
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PTGES O14684 1/20 0.40
SOS1 Q07889 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
TNF P01375 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15366767 1.00 MEN1 (0.52) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL4264384 0.89 CES1 (0.50) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL2725777 0.87 MEN1 (0.52) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL4600511 0.86 CES1 (0.48) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL27862693 0.84 KDM4E (0.44) MEN1KMT2AKDM4EALDH1A1HPGD
Biphenyl SCHEMBL28230506 0.83 CES1 (0.49) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL20250411 0.82 PARP1 (0.41) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL2086646 0.82 ALOX5 (0.55) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL29682050 0.82 ALOX5 (0.55) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL300507 0.81 ALOX5 (0.57) MEN1KMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 CN disclosed