Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.44 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325041 | 1.00 | PDE10A (0.44) | PDE10AAXLPRKCIDYRK1AADORA2A | |
| SCHEMBL15941531 | 0.79 | DYRK1A (0.41) | PDE10ADYRK1AADORA2AADORA1JAK1 | |
| SCHEMBL25876329 | 0.78 | P2RX7 (0.35) | JAK1 | |
| SCHEMBL11917994 | 0.76 | JAK1 (0.37) | DYRK1AADORA2AADORA1JAK1 | |
| SCHEMBL5925913 | 0.76 | LRRK2 (0.40) | JAK1 | |
| SCHEMBL26661507 | 0.76 | JAK1 (0.39) | DYRK1AADORA2AADORA1JAK1 | |
| SCHEMBL2253914 | 0.74 | PARP1 (0.33) | AXLPRKCIJAK1 | |
| SCHEMBL29700716 | 0.74 | PRKCI (0.44) | AXLPRKCIDYRK1AADORA2AADORA1 | |
| SCHEMBL691603 | 0.74 | PRKCI (0.44) | AXLPRKCIDYRK1AADORA2AADORA1 | |
| SCHEMBL30095824 | 0.72 | PDE10A (0.44) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |