Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.77 |
| ▸ | FBP1 | P09467 | 2/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 3/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Faicar SCHEMBL851406 | 0.87 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| Faicar SCHEMBL4360247 | 0.87 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL30388429 | 0.81 | ATIC (0.67) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL20276955 | 0.79 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| Mizoribine Monophosphate SCHEMBL12727826 | 0.79 | ATIC (0.80) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL849848 | 0.79 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL1230585 | 0.79 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL4359472 | 0.79 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| Mizoribine Monophosphate SCHEMBL16329889 | 0.79 | ATIC (0.80) | ATICFBP1TAS1R3TAS1R1DNPH1 | |
| SCHEMBL20134003 | 0.79 | ATIC (1.00) | ATICFBP1TAS1R3TAS1R1DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119220474-B | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119220474-A | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2024-12-31 | — | — | CN | claimed |
| US-20240124907-A1 | Engineered Biosynthetic Pathways for Production of Histamine by Fermentation | ZYMERGEN INC. (US) | 2024-04-18 | — | — | US | claimed |
| US-11739355-B2 | Engineered biosynthetic pathways for production of histamine by fermentation | ZYMERGEN INC. (US) | 2023-08-29 | — | — | US | claimed |
| CN-119220474-B | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-119220474-A | Escherichia coli genetically engineered bacterium for producing L-histidine through fermentation, method and application | 天津科技大学 | 2024-12-31 | — | — | CN | disclosed |
| US-20240124907-A1 | Engineered Biosynthetic Pathways for Production of Histamine by Fermentation | ZYMERGEN INC. (US) | 2024-04-18 | — | — | US | disclosed |
| US-11739355-B2 | Engineered biosynthetic pathways for production of histamine by fermentation | ZYMERGEN INC. (US) | 2023-08-29 | — | — | US | disclosed |