Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 14/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544669 | 0.81 | SLC6A2 (0.46) | KAT2BBPTF | |
| SCHEMBL30544664 | 0.80 | MAP4K4 (0.41) | MAP4K4NLRP3 | |
| SCHEMBL30544681 | 0.80 | MAP4K4 (0.41) | MAP4K4NLRP3 | |
| SCHEMBL30544699 | 0.80 | MAP4K4 (0.41) | MAP4K4NLRP3 | |
| SCHEMBL30544688 | 0.72 | PARP1 (0.34) | MAP4K4 | |
| SCHEMBL25152655 | 0.69 | ABL1 (0.43) | — | |
| SCHEMBL25151852 | 0.69 | ABL1 (0.43) | — | |
| SCHEMBL25151880 | 0.69 | ABL1 (0.43) | — | |
| SCHEMBL30544690 | 0.69 | HTR3A (0.52) | — | |
| SCHEMBL31427034 | 0.67 | LRRK2 (0.35) | KAT2BBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635371-A | Polycyclic pyridazinone derivative serving as SOS1 inhibitor, and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |