Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 8/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521151 | 1.00 | LMNA (0.38) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL29351575 | 0.95 | CYP2D6 (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL29847089 | 0.95 | CYP2D6 (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL30355025 | 0.95 | CYP2D6 (0.35) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL30545074 | 0.91 | CYP2D6 (0.33) | LMNACYP2D6SPHK1GMNNPOLB | |
| Triphosphate SCHEMBL30619686 | 0.85 | SMPD1 (0.42) | FDPSGGPS1 | |
| SCHEMBL13730862 | 0.81 | CYP2D6 (0.41) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL21694053 | 0.80 | LMNA (0.41) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL30203459 | 0.79 | LMNA (0.39) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL30203533 | 0.79 | LMNA (0.39) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645511-B1 | POLYMER COMPOSITIONS STABILIZED WITH ORGANOPOLYSULFIDES | ARKEMA INC (US) | 2023-08-16 | — | — | EP | disclosed |