Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769560 | 0.83 | FSCN1 (0.51) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL7612739 | 0.77 | FSCN1 (0.66) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL11248092 | 0.75 | FSCN1 (0.57) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL7710336 | 0.72 | FSCN1 (0.44) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL8196854 | 0.68 | FSCN1 (0.47) | FSCN1TSHRCASP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10485955 | 0.67 | FSCN1 (0.56) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL653173 | 0.67 | FSCN1 (0.51) | FSCN1TSHRCASP1SMN1; SMN2MAPT | |
| SCHEMBL30545003 | 0.67 | POLB (0.35) | TSHRKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL1432108 | 0.66 | FSCN1 (0.55) | FSCN1TSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL10579443 | 0.66 | TSHR (0.59) | TSHRCASP1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655536-A | Class N 1 -aryl-3-fluoroalkyl-5-fluoropyrazole compound, and preparation method and application thereof | 天津大学 | 2023-08-29 | — | — | CN | disclosed |