Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545009 | 0.79 | LMNA (0.38) | ALDH1A1MEN1KMT2ATP53KDM4E | |
| SCHEMBL19527666 | 0.76 | POLB (0.39) | POLBALDH1A1TDP1GAAHTT | |
| SCHEMBL30545021 | 0.75 | ALOX5 (0.37) | ALDH1A1HTTKDM4ETSHR | |
| SCHEMBL27902968 | 0.75 | GAA (0.39) | POLBALDH1A1TDP1GAAHTT | |
| SCHEMBL30545032 | 0.73 | HSD17B1 (0.41) | ALDH1A1HTTMEN1KMT2ATP53 | |
| SCHEMBL15347758 | 0.72 | ALDH1A1 (0.39) | POLBALDH1A1TDP1GAAHTT | |
| SCHEMBL20264395 | 0.69 | POLB (0.45) | POLBGAAHTTMEN1KMT2A | |
| SCHEMBL29940563 | 0.69 | POLB (0.45) | POLBGAAHTTMEN1KMT2A | |
| SCHEMBL10363554 | 0.68 | ALOX5 (0.41) | POLBALDH1A1TDP1GAAHTT | |
| SCHEMBL30545014 | 0.67 | FSCN1 (0.47) | ALDH1A1GAAHTTTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655536-A | Class N 1 -aryl-3-fluoroalkyl-5-fluoropyrazole compound, and preparation method and application thereof | 天津大学 | 2023-08-29 | — | — | CN | disclosed |