Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286430 | 0.93 | MAPT (1.00) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25199853 | 0.93 | MAPT (1.00) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2286422 | 0.93 | MAPT (1.00) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30383814 | 0.93 | MAPT (1.00) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31233040 | 0.85 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2279010 | 0.85 | MAPT (0.85) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30383606 | 0.85 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25279735 | 0.85 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25208509 | 0.85 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30383546 | 0.85 | MAPT (0.85) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269104-B | Chalcone analogue and application thereof | 温州医科大学 | 2023-08-04 | — | — | CN | disclosed |