Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279735 | 1.00 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30383606 | 1.00 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25208509 | 1.00 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31233074 | 0.93 | MAPT (0.74) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7656609 | 0.93 | MAPT (0.74) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30383986 | 0.93 | MAPT (0.74) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7656614 | 0.93 | MAPT (0.74) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30545301 | 0.85 | MAPT (0.88) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16490919 | 0.82 | MAOB (0.74) | MAPTCYP3A4MAOAMAOBSMN1; SMN2 | |
| SCHEMBL30383843 | 0.82 | MAOB (0.74) | MAPTCYP3A4MAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |