Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL122091 | 0.95 | CA4 (0.39) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28534382 | 0.91 | CA1 (0.36) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28790281 | 0.91 | CA1 (0.36) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL7062462 | 0.91 | CA4 (0.42) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL8995980 | 0.91 | — | — | |
| Bicarbonate SCHEMBL7061607 | 0.86 | CA4 (0.39) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL10525004 | 0.86 | CA4 (0.50) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL11096099 | 0.86 | CA4 (0.50) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL22800564 | 0.86 | CA4 (0.50) | CA1CA4FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL419170 | 0.86 | CA4 (0.39) | CA1CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528978-A | Silica-alumina composition comprising 1-30 wt% crystalline basic ammonium aluminum carbonate and process for preparing the same | 雪佛龙美国公司 | 2023-08-01 | — | — | CN | disclosed |