Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708631 | 0.87 | LMNA (0.42) | LMNAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL2008909 | 0.86 | LMNA (0.39) | LMNAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL2008911 | 0.86 | LMNA (0.39) | LMNAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL878441 | 0.73 | BTN3A1 (0.43) | ALDH1A1KDM4ETDP1HTT | |
| SCHEMBL2012770 | 0.73 | ELANE (0.40) | LMNAMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL2012767 | 0.73 | ELANE (0.40) | LMNAMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL2008560 | 0.73 | LMNA (0.41) | LMNAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL2008561 | 0.73 | LMNA (0.41) | LMNAKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL16223471 | 0.72 | CA12 (0.37) | SMN1; SMN2MMP2CA14CA12MMP9 | |
| SCHEMBL16223469 | 0.72 | CA12 (0.37) | SMN1; SMN2MMP2CA14CA12MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731098-A | Nucleoside phosphoramidate prodrugs | 吉利德科学公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116731099-A | Nucleoside phosphoramidate prodrugs | 吉利德科学公司 | 2023-09-12 | — | — | CN | claimed |