Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 7/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302383 | 1.00 | KDM4E (0.50) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL25254404 | 0.89 | KDM4E (0.50) | KDM4ENEK2CHRM4HCRTR2TMPRSS15 | |
| SCHEMBL30547539 | 0.89 | KDM4E (0.50) | KDM4ENEK2CHRM4HCRTR2TMPRSS15 | |
| SCHEMBL20565681 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| Hydrochloric Acid SCHEMBL20565233 | 0.81 | KDM4E (0.55) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL20565611 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL20564608 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL25294566 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL30338757 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL31111338 | 0.78 | KDM4E (0.48) | KDM4EHSD17B10USP2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547281-A | Isoxazolidines as RIPK1 inhibitors and uses thereof | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |