Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134938 | 0.75 | POLB (0.57) | POLBP2RX7NPSR1CYP1A2CYP3A4 | |
| SCHEMBL26134434 | 0.69 | POLB (0.59) | POLBP2RX7MEN1KMT2ACYP1A2 | |
| SCHEMBL20939799 | 0.69 | NPC1 (0.49) | POLBP2RX7RAB9AMEN1KMT2A | |
| SCHEMBL4325553 | 0.68 | P2RX7 (0.47) | POLBP2RX7SMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL26130191 | 0.68 | POLB (0.58) | POLBP2RX7RAB9AMEN1KMT2A | |
| SCHEMBL26136588 | 0.68 | POLB (0.57) | POLBP2RX7RAB9AMEN1KMT2A | |
| SCHEMBL26135256 | 0.68 | POLB (0.57) | POLBP2RX7MEN1KMT2ANPSR1 | |
| SCHEMBL26134968 | 0.68 | POLB (0.57) | POLBP2RX7RAB9AMEN1KMT2A | |
| SCHEMBL26134773 | 0.67 | POLB (0.56) | POLBP2RX7MEN1KMT2ANPSR1 | |
| SCHEMBL26134661 | 0.67 | POLB (0.56) | POLBP2RX7CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504728-A1 | PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023187182-A1 | PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-05 | — | — | WO | disclosed |