Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285879 | 1.00 | CYP11B2 (0.30) | CYP11B2 | |
| SCHEMBL18635078 | 0.85 | CYP11B2 (0.33) | CYP11B2 | |
| SCHEMBL16196047 | 0.82 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL16196201 | 0.82 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL6921068 | 0.82 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL14991534 | 0.79 | CYP11B1 (0.35) | CYP11B2 | |
| SCHEMBL17121949 | 0.77 | — | — | |
| SCHEMBL25905726 | 0.76 | — | — | |
| SCHEMBL6921443 | 0.76 | — | — | |
| SCHEMBL25777383 | 0.75 | CYP11B2 (0.30) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448533-A1 | <SUP2/>? <SUB2/>?V?PYRIDINE-3-CARBOXYLATE COMPOUNDS AS CA1.2 ACTIVATORS | Novartis AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-118510782-A | As CaV1.2 Pyridine-3-carboxylic acid ester Compounds of activators | 诺华股份有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023111799-A1 | PYRIDINE-3-CARBOXYLATE COMPOUNDS AS CaV1.2 ACTIVATORS | NOVARTIS AG (CH) | 2023-06-22 | — | — | WO | disclosed |