Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323968 | 1.00 | ACACB (0.33) | ACACBGRM2TIPARPFGFR1FGFR4 | |
| SCHEMBL25323965 | 1.00 | ACACB (0.33) | ACACBGRM2TIPARPFGFR1FGFR4 | |
| SCHEMBL25320929 | 0.84 | GRM2 (0.35) | GRM2TIPARPFGFR1FGFR4 | |
| SCHEMBL30550705 | 0.84 | GRM2 (0.35) | GRM2TIPARPFGFR1FGFR4 | |
| SCHEMBL25320933 | 0.84 | GRM2 (0.35) | GRM2TIPARPFGFR1FGFR4 | |
| SCHEMBL25321334 | 0.80 | TIPARP (0.53) | TIPARP | |
| SCHEMBL25321340 | 0.80 | TIPARP (0.53) | TIPARP | |
| SCHEMBL25319165 | 0.76 | TIPARP (0.39) | TIPARP | |
| SCHEMBL25319163 | 0.76 | TIPARP (0.39) | TIPARP | |
| SCHEMBL25321367 | 0.76 | AAK1 (0.41) | ACACBTIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |