Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.30 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550705 | 1.00 | GRM2 (0.35) | GRM2FGFR1FGFR4IDH1PIK3C2A | |
| SCHEMBL25320929 | 1.00 | GRM2 (0.35) | GRM2FGFR1FGFR4IDH1PIK3C2A | |
| SCHEMBL25323968 | 0.84 | ACACB (0.33) | GRM2FGFR1FGFR4TIPARP | |
| SCHEMBL30550679 | 0.84 | ACACB (0.33) | GRM2FGFR1FGFR4TIPARP | |
| SCHEMBL25323965 | 0.84 | ACACB (0.33) | GRM2FGFR1FGFR4TIPARP | |
| SCHEMBL25321340 | 0.82 | TIPARP (0.53) | TIPARP | |
| SCHEMBL25321334 | 0.82 | TIPARP (0.53) | TIPARP | |
| SCHEMBL25319165 | 0.77 | TIPARP (0.39) | TIPARP | |
| SCHEMBL25319163 | 0.77 | TIPARP (0.39) | TIPARP | |
| SCHEMBL25898569 | 0.74 | GRM2 (0.41) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459922-B2 | PARP7 inhibitors | GILEAD SCIENCES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-20230365529-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459922-B2 | PARP7 inhibitors | PARP1, PARP11, PARP2 | GRM2 4803/4885FGFR1 2159/4885FGFR4 2497/4885 |
| US-20230365529-A1 | PARP7 INHIBITORS | PARP1, PARP11, PARP2 | GRM2 4803/4885FGFR1 2159/4885FGFR4 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.