Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 12/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550711 | 1.00 | TIPARP (0.41) | TIPARPDGAT1MCHR1BRD4GRM2 | |
| SCHEMBL25321245 | 1.00 | TIPARP (0.41) | TIPARPDGAT1MCHR1BRD4GRM2 | |
| SCHEMBL30550644 | 0.92 | TIPARP (0.45) | TIPARPDGAT1GRM2 | |
| SCHEMBL25320156 | 0.92 | TIPARP (0.45) | TIPARPDGAT1GRM2 | |
| SCHEMBL25320149 | 0.92 | TIPARP (0.45) | TIPARPDGAT1GRM2 | |
| SCHEMBL31058417 | 0.85 | TIPARP (0.41) | TIPARPDGAT1 | |
| SCHEMBL25322428 | 0.82 | TIPARP (0.59) | TIPARP | |
| SCHEMBL25320452 | 0.82 | TIPARP (0.59) | TIPARP | |
| SCHEMBL25318306 | 0.82 | TIPARP (0.59) | TIPARP | |
| SCHEMBL30550706 | 0.82 | TIPARP (0.59) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |