Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 15/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.31 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320149 | 1.00 | TIPARP (0.45) | TIPARPDGAT1PARP1CYP2C9PARP14 | |
| SCHEMBL25320156 | 1.00 | TIPARP (0.45) | TIPARPDGAT1PARP1CYP2C9PARP14 | |
| SCHEMBL25321245 | 0.92 | TIPARP (0.41) | TIPARPDGAT1GRM2 | |
| SCHEMBL30550711 | 0.92 | TIPARP (0.41) | TIPARPDGAT1GRM2 | |
| SCHEMBL30550713 | 0.92 | TIPARP (0.41) | TIPARPDGAT1GRM2 | |
| SCHEMBL25321909 | 0.89 | TIPARP (0.36) | TIPARPDGAT1PARP1CYP2C9PARP14 | |
| SCHEMBL31362881 | 0.89 | TIPARP (0.34) | TIPARP | |
| SCHEMBL30550610 | 0.89 | TIPARP (0.36) | TIPARPDGAT1PARP1CYP2C9PARP14 | |
| SCHEMBL25321896 | 0.89 | TIPARP (0.36) | TIPARPDGAT1PARP1CYP2C9PARP14 | |
| SCHEMBL31058417 | 0.86 | TIPARP (0.41) | TIPARPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |