Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 9/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322327 | 1.00 | TIPARP (0.42) | TIPARPKITFLT3GRM4 | |
| SCHEMBL26804516 | 0.87 | TIPARP (0.33) | TIPARPGRM4 | |
| SCHEMBL26658809 | 0.86 | TIPARP (0.44) | TIPARPKITFLT3GRM4 | |
| SCHEMBL26658767 | 0.86 | TIPARP (0.44) | TIPARPKITFLT3GRM4 | |
| SCHEMBL25904508 | 0.86 | TIPARP (0.44) | TIPARPKITFLT3GRM4 | |
| SCHEMBL25904618 | 0.86 | TIPARP (0.45) | TIPARPKITFLT3GRM4 | |
| SCHEMBL26658685 | 0.86 | TIPARP (0.45) | TIPARPKITFLT3GRM4 | |
| SCHEMBL26658718 | 0.86 | TIPARP (0.46) | TIPARPKITFLT3GRM4 | |
| SCHEMBL25904512 | 0.86 | TIPARP (0.43) | TIPARPKITFLT3GRM4 | |
| SCHEMBL25904734 | 0.85 | TIPARP (0.44) | TIPARPKITFLT3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |