Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PDE8A | O60658 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774516 | 1.00 | HPGD (0.54) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6950422 | 0.84 | HPGD (0.52) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1667447 | 0.83 | HPGD (0.51) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5465357 | 0.81 | HPGD (0.64) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30834262 | 0.79 | ADORA2A (0.49) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16774098 | 0.79 | MEN1 (0.55) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16774386 | 0.79 | ADORA2A (0.49) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30881405 | 0.78 | L3MBTL1 (0.56) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL27244169 | 0.78 | L3MBTL1 (0.56) | HPGDNR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL22533518 | 0.78 | HDAC6 (0.41) | MEN1KMT2AADORA2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448190-B | Substituted indole compounds | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | disclosed |