Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 8/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 3/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27053264 | 1.00 | LMNA (0.44) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL31424848 | 0.92 | ESR2 (0.40) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL23580642 | 0.87 | ESR2 (0.42) | ESR2NR1H2F12HDAC1HDAC6 | |
| SCHEMBL23580395 | 0.87 | ESR2 (0.42) | ESR2NR1H2F12HDAC1HDAC6 | |
| SCHEMBL404753 | 0.84 | BAZ2B (0.48) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL27053267 | 0.81 | SMARCA2 (0.52) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL22412978 | 0.80 | LMNA (0.46) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL21114757 | 0.77 | BAZ2B (0.71) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL18103922 | 0.77 | BAZ2B (0.43) | LMNAPABPC1ATMSMN1; SMN2ESR2 | |
| SCHEMBL30682952 | 0.76 | DDB1 (0.44) | ESR2BAZ2BNR1H2F12HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |