Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 7/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.65 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.65 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322173 | 1.00 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25323518 | 0.86 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25322731 | 0.72 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL31052622 | 0.65 | PARP2 (0.48) | PARP2ALDH1A1IDO1TDO2MAPT | |
| SCHEMBL30884726 | 0.64 | PARP2 (0.46) | PARP2ALDH1A1NPSR1IDO1TDO2 | |
| SCHEMBL3996134 | 0.62 | PARP2 (0.45) | PARP2ALDH1A1NPSR1IDO1TDO2 | |
| SCHEMBL3996113 | 0.62 | PARP2 (0.45) | PARP2ALDH1A1NPSR1IDO1TDO2 | |
| SCHEMBL30884722 | 0.62 | PARP2 (0.45) | PARP2ALDH1A1IDO1TDO2MAPT | |
| SCHEMBL25325363 | 0.62 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25322921 | 0.62 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469046-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | Oulun Yliopisto (FI) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |