Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 7/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.69 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.69 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.59 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.59 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.59 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.59 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.59 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.59 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322173 | 0.86 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25322731 | 0.75 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL11749369 | 0.67 | DYRK1A (0.54) | PARP2ADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL25325363 | 0.64 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25325548 | 0.64 | PARP2 (0.59) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25322921 | 0.64 | PARP2 (1.00) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL25324132 | 0.63 | PARP2 (0.74) | PARP2TNKS2PARP15PARP10TNKS | |
| SCHEMBL3057508 | 0.61 | ADORA2A (0.61) | PARP2ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL9753618 | 0.60 | ALDH1A1 (0.56) | ADORA2AADORA2BALDH1A1KDM4ENPC1 | |
| SCHEMBL30675555 | 0.60 | ADORA3 (0.51) | ADORA2AADORA2BALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2025-06-05 | — | — | US | disclosed |
| EP-4469046-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | Oulun Yliopisto (FI) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | NAMPT, NADK, NQO1 | PARP2 15/4885TNKS2 29/4885PARP15 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.