Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | LCAT | P04180 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | USP19 | O94966 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326208 | 1.00 | GRM1 (0.33) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL25325260 | 0.89 | ACACB (0.35) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL30553216 | 0.89 | ACACB (0.35) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL30553284 | 0.88 | ACACB (0.35) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL25324716 | 0.88 | MGLL (0.31) | MGLLUSP19 | |
| SCHEMBL25325047 | 0.88 | ACACB (0.35) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL25323304 | 0.83 | MGLL (0.39) | MGLL | |
| SCHEMBL25323935 | 0.83 | LCAT (0.36) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL25325885 | 0.83 | LCAT (0.36) | GRM1ACACBAVPR2MGLLLCAT | |
| SCHEMBL30553142 | 0.83 | LCAT (0.36) | GRM1ACACBAVPR2MGLLLCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |