Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.33 |
| ▸ | OXTR | P30559 | 9/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324147 | 1.00 | MGLL (0.37) | MGLLAVPR2OXTRAVPR1A | |
| SCHEMBL25325214 | 0.94 | MGLL (0.34) | MGLLAVPR2OXTR | |
| SCHEMBL30553259 | 0.94 | MGLL (0.34) | MGLLAVPR2OXTR | |
| SCHEMBL25327491 | 0.88 | MGLL (0.40) | MGLL | |
| SCHEMBL25325125 | 0.88 | MGLL (0.41) | MGLLAVPR2OXTRAVPR1A | |
| SCHEMBL25325303 | 0.86 | MGLL (0.37) | MGLL | |
| SCHEMBL30553185 | 0.85 | MGLL (0.36) | MGLL | |
| SCHEMBL25325185 | 0.85 | MGLL (0.36) | MGLL | |
| SCHEMBL25326162 | 0.84 | MGLL (0.36) | MGLL | |
| SCHEMBL25324301 | 0.83 | MGLL (0.36) | MGLLAVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |