Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 7/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324071 | 1.00 | CNR1 (0.36) | CNR1L3MBTL1MGLLAKR1C3RORC | |
| SCHEMBL25326299 | 0.87 | CNR1 (0.46) | CNR1L3MBTL1AKR1C3CACNA1B | |
| SCHEMBL25328257 | 0.87 | CNR1 (0.40) | CNR1L3MBTL1MGLLAKR1C3CACNA1B | |
| SCHEMBL25324457 | 0.87 | GAA (0.39) | CNR1MGLLAKR1C3 | |
| SCHEMBL25326395 | 0.81 | CACNA1B (0.35) | MGLLRORCCACNA1B | |
| SCHEMBL30012332 | 0.80 | MGLL (0.55) | CNR1L3MBTL1MGLLAKR1C3NAMPT | |
| SCHEMBL30553208 | 0.80 | MGLL (0.42) | MGLL | |
| SCHEMBL25324678 | 0.80 | MGLL (0.42) | MGLL | |
| SCHEMBL25325171 | 0.79 | AKR1C3 (0.38) | AKR1C3 | |
| SCHEMBL25325330 | 0.79 | DPP4 (0.42) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |