Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.55 |
| ▸ | TACR3 | P29371 | 15/20 | 0.49 |
| ▸ | TACR2 | P21452 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22284218 | 1.00 | MAPK1 (0.55) | MAPK1MAPK3TACR3TACR2CYP1A2 | |
| SCHEMBL20931757 | 1.00 | MAPK1 (0.55) | MAPK1MAPK3TACR3TACR2CYP1A2 | |
| SCHEMBL30554283 | 0.92 | MAPK1 (0.59) | MAPK1MAPK3TACR3 | |
| SCHEMBL20916798 | 0.92 | MAPK1 (0.59) | MAPK1MAPK3TACR3 | |
| SCHEMBL20931407 | 0.92 | MAPK1 (0.59) | MAPK1MAPK3TACR3 | |
| SCHEMBL30554325 | 0.91 | MAPK1 (0.48) | MAPK1MAPK3 | |
| SCHEMBL20931525 | 0.91 | MAPK1 (0.48) | MAPK1MAPK3 | |
| SCHEMBL22284205 | 0.91 | MAPK1 (0.48) | MAPK1MAPK3 | |
| SCHEMBL20920102 | 0.91 | MAPK1 (0.49) | MAPK1MAPK3 | |
| SCHEMBL30554370 | 0.91 | MAPK1 (0.49) | MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |