Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337330 | 1.00 | PIK3CA (0.50) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL25337886 | 0.90 | PLK1 (0.52) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL30554568 | 0.90 | PLK1 (0.52) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL30554593 | 0.86 | PIK3CA (0.55) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL25340053 | 0.86 | PIK3CA (0.55) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL25335900 | 0.83 | PIK3CA (0.58) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL30554566 | 0.83 | PIK3CA (0.58) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 | |
| SCHEMBL25338135 | 0.82 | MAPK8 (0.55) | CDK2GSK3BCDK4ABL1BCR | |
| SCHEMBL30554526 | 0.82 | MAPK8 (0.55) | CDK2GSK3BCDK4ABL1BCR | |
| SCHEMBL25336527 | 0.81 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118891251-A | Aryl hydrocarbon receptor agonists and uses thereof | 奈可萨斯医药有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, NR1H4, CNR1 | PIK3CA 3736/4885PIK3CB 4402/4885PIK3CG 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.