Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | GSK3B | P49841 | 4/20 | 0.51 |
| ▸ | CDK4 | P11802 | 3/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.47 |
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340053 | 1.00 | PIK3CA (0.55) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL25335900 | 0.86 | PIK3CA (0.58) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL30554566 | 0.86 | PIK3CA (0.58) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL30554571 | 0.86 | PIK3CA (0.50) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL25337330 | 0.86 | PIK3CA (0.50) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL25336527 | 0.83 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL30554554 | 0.83 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL25337070 | 0.83 | KCNH2 (0.51) | MEN1KMT2ACDK2GSK3BCDK4 | |
| SCHEMBL30554510 | 0.83 | KCNH2 (0.51) | MEN1KMT2ACDK2GSK3BCDK4 | |
| SCHEMBL25337886 | 0.82 | PLK1 (0.52) | PIK3CAPIK3CBPIK3CGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118891251-A | Aryl hydrocarbon receptor agonists and uses thereof | 奈可萨斯医药有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |