Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 7/20 | 0.48 |
| ▸ | CCNH | P51946 | 7/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.48 |
| ▸ | CCNK | O75909 | 4/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.48 |
| ▸ | CDK9 | P50750 | 4/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 3/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22104351 | 1.00 | EGFR (0.59) | EGFRCDK1KDRCDK7CCNH | |
| SCHEMBL30556289 | 0.91 | EGFR (0.70) | EGFRCDK1KDRCCNT1CCNK | |
| SCHEMBL22104361 | 0.91 | EGFR (0.70) | EGFRCDK1KDRCCNT1CCNK | |
| SCHEMBL30556290 | 0.90 | EGFR (0.62) | EGFRCDK1KDRCCNT1CCNK | |
| SCHEMBL22104432 | 0.90 | EGFR (0.62) | EGFRCDK1KDRCCNT1CCNK | |
| SCHEMBL22089640 | 0.83 | EGFR (0.54) | EGFRCDK1KDRCDK7CCNH | |
| SCHEMBL30556292 | 0.83 | EGFR (0.54) | EGFRCDK1KDRCDK7CCNH | |
| SCHEMBL22089721 | 0.82 | EGFR (0.64) | EGFRCDK1KDRCDK7CCNH | |
| SCHEMBL30556296 | 0.82 | EGFR (0.64) | EGFRCDK1KDRCDK7CCNH | |
| SCHEMBL517889 | 0.81 | EGFR (0.81) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166110-B | 2-aminopyrimidine compound and application thereof | 暨南大学 | 2023-08-11 | — | — | CN | disclosed |