Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339186 | 0.87 | KMT2A (0.47) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL17339063 | 0.86 | KMT2A (0.46) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL28211031 | 0.82 | KMT2A (0.43) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL30671841 | 0.77 | CYP19A1 (0.43) | KMT2AMAPTALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL30886775 | 0.75 | CA12 (0.51) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL16655014 | 0.75 | CA12 (0.51) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL17339081 | 0.75 | KMT2A (0.50) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL29533984 | 0.75 | KMT2A (0.50) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL30556278 | 0.74 | NOD2 (0.38) | KMT2AMEN1RECQLRPS6KA5RPS6KA4 | |
| SCHEMBL29520629 | 0.73 | MEN1 (0.56) | KMT2AKDM4EMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166110-B | 2-aminopyrimidine compound and application thereof | 暨南大学 | 2023-08-11 | — | — | CN | disclosed |