Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111824 | 1.00 | HRH4 (0.52) | HRH4POLBEIF4A3KMT2A | |
| SCHEMBL22620755 | 0.85 | HRH4 (0.56) | HRH4POLBKMT2A | |
| SCHEMBL6142001 | 0.85 | HRH4 (0.70) | HRH4 | |
| SCHEMBL23712320 | 0.83 | HRH4 (0.54) | HRH4POLB | |
| SCHEMBL23111896 | 0.83 | CNR1 (0.42) | HRH4POLBEIF4A3KMT2A | |
| SCHEMBL30556366 | 0.83 | CNR1 (0.42) | HRH4POLBEIF4A3KMT2A | |
| SCHEMBL22620614 | 0.81 | HRH4 (0.54) | HRH4 | |
| SCHEMBL22615532 | 0.77 | HRH4 (0.48) | HRH4POLB | |
| SCHEMBL22615157 | 0.77 | HRH4 (0.48) | HRH4POLBKMT2A | |
| SCHEMBL29465466 | 0.77 | HRH4 (0.48) | HRH4POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | IDO1, IDO2, INMT | HRH4 1210/4885POLB 4235/4885EIF4A3 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.