Prothixene

Prothixene

SCHEMBL30557147

CN(C)CCC=C1c2ccccc2Sc2ccccc21

nearest known ligand 0.76

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.76
HRH1 P35367 7/20 0.76
KCNH2 Q12809 7/20 0.76
LMNA P02545 6/20 0.76
CHRM2 P08172 6/20 0.76
CHRM1 P11229 6/20 0.76
DRD2 P14416 6/20 0.76
SLC6A4 P31645 6/20 0.76
ADRA1A P35348 6/20 0.76
DRD3 P35462 6/20 0.76
CYP2D6 P10635 5/20 0.76
ADRA2A P08913 5/20 0.76
HTR1A P08908 5/20 0.76
CYP3A4 P08684 4/20 0.76
CYP1A2 P05177 4/20 0.76
MC3R P41968 4/20 0.76
DRD1 P21728 4/20 0.76
SLC6A3 Q01959 3/20 0.76
MTOR P42345 3/20 0.76
TP53 P04637 3/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prothixene SCHEMBL623020 1.00 SLC6A2 (0.76) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL29626798 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL94236 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL94235 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL29357955 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL24133 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL30383335 0.87 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL455758 0.86 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL455759 0.86 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2
Chlorprothixene SCHEMBL29857011 0.86 LMNA (1.00) SLC6A2HRH1KCNH2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
CN-116583310-A Surgical system and method of use 美敦力公司 2023-08-11 CN disclosed