SCHEMBL30557162

SCHEMBL30557162

N[C@H](CO)c1ccc(Cl)c(-c2ncnn2C(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20899952 1.00 GABRG2 (0.33) GABRG2GABRB3GABRA5MAPK1
SCHEMBL20899954 1.00 GABRG2 (0.33) GABRG2GABRB3GABRA5MAPK1
Hydrochloric Acid SCHEMBL21112528 0.99 GABRG2 (0.32) GABRG2GABRB3GABRA5MAPK1
Hydrochloric Acid SCHEMBL20899898 0.99 GABRG2 (0.32) GABRG2GABRB3GABRA5MAPK1
SCHEMBL20900146 0.86 MAPK1 (0.33) MAPK1
SCHEMBL20899981 0.86 MAPK1 (0.33) MAPK1
SCHEMBL20900246 0.84 GABRG2 (0.34) GABRG2GABRB3GABRA5
SCHEMBL20899894 0.82 EGLN2 (0.32)
SCHEMBL20908251 0.82 EGLN2 (0.32)
SCHEMBL30557360 0.82 EGLN2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111212832-B 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors 吉利德科学公司 2023-09-15 CN disclosed