Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 8/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557348 | 0.81 | EP300 (0.39) | EP300CREBBPRETBRD4 | |
| SCHEMBL30557428 | 0.80 | EP300 (0.38) | EP300CREBBPRETBRD4 | |
| SCHEMBL21150362 | 0.77 | JAK1 (0.36) | EP300JAK1CREBBPRETBRD4 | |
| SCHEMBL20907580 | 0.77 | JAK1 (0.36) | EP300JAK1CREBBPRETBRD4 | |
| SCHEMBL17806585 | 0.68 | CREBBP (0.40) | EP300CREBBPBRD4 | |
| SCHEMBL28403736 | 0.65 | MKNK1 (0.35) | EP300CREBBPRETBRD4 | |
| SCHEMBL28403738 | 0.65 | MKNK1 (0.35) | EP300CREBBPRETBRD4 | |
| SCHEMBL21150320 | 0.65 | MKNK1 (0.34) | EP300CREBBPRETBRD4 | |
| SCHEMBL23535741 | 0.64 | CA1 (0.43) | CREBBPBRD4 | |
| SCHEMBL30557222 | 0.63 | BRD4 (0.35) | EP300CREBBPRETBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |