Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050030 | 1.00 | HPGD (0.38) | HPGDSMN1; SMN2TACR1LMNACTNNB1 | |
| SCHEMBL3055716 | 1.00 | HPGD (0.38) | HPGDSMN1; SMN2TACR1LMNACTNNB1 | |
| SCHEMBL3044581 | 0.92 | CTNNB1 (0.42) | HPGDLMNACTNNB1WNT3AALDH1A1 | |
| SCHEMBL3039886 | 0.92 | CTNNB1 (0.42) | HPGDLMNACTNNB1WNT3AALDH1A1 | |
| SCHEMBL3051127 | 0.91 | C5AR1 (0.38) | LMNAALDH1A1MT-CO2MEN1MAPT | |
| SCHEMBL3040813 | 0.91 | ABCB1 (0.35) | TACR1LMNACTNNB1WNT3AMAPT | |
| SCHEMBL3051174 | 0.91 | C5AR1 (0.38) | LMNAALDH1A1MT-CO2MEN1MAPT | |
| SCHEMBL3040903 | 0.91 | ABCB1 (0.35) | TACR1LMNACTNNB1WNT3AMAPT | |
| SCHEMBL3040854 | 0.88 | SMN1; SMN2 (0.35) | HPGDSMN1; SMN2LMNACTNNB1WNT3A | |
| SCHEMBL3047594 | 0.88 | SMN1; SMN2 (0.35) | HPGDSMN1; SMN2LMNACTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222396-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222396-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | CYP11B2, CYP11B1, BBC3 | HPGD 756/4885SMN1; SMN2 2299/4885TACR1 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.