Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 7/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28885757 | 0.95 | ABCB1 (0.61) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30557942 | 0.91 | ABCB1 (0.55) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30557945 | 0.91 | ABCB1 (0.52) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30557947 | 0.87 | ALDH1A1 (0.54) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30557936 | 0.86 | ABCB1 (0.54) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30022715 | 0.85 | ALDH1A1 (0.56) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30023178 | 0.83 | ALDH1A1 (0.60) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30557929 | 0.82 | ABCB1 (0.51) | ABCB1KCNK3KCNK9 | |
| SCHEMBL30557933 | 0.82 | CYP3A4 (0.56) | ABCB1ALDH1A1NPSR1KCNK3KCNK9 | |
| SCHEMBL30023054 | 0.80 | ALDH1A1 (0.56) | ABCB1ALDH1A1NPSR1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160313-B | 2-phenylimidazole [1,2-a ] pyridine compound, composition containing same and application of 2-phenylimidazole [1,2-a ] pyridine compound and composition | 中国药科大学 | 2023-09-05 | — | — | CN | disclosed |