Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247484 | 1.00 | KDM4E (0.50) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20803565 | 0.80 | NR4A2 (0.53) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL4820228 | 0.79 | KDM4E (0.56) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1504248 | 0.77 | MEN1 (0.48) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1368260 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29582392 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL160155 | 0.76 | AURKA (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| Benzoylenurea SCHEMBL4559940 | 0.76 | ALDH1A1 (0.50) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29414293 | 0.76 | AURKA (0.61) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6887071 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874468-A | Synthesis and application of small molecular compound with 2-pyridine substituted formamide structure | 江西中医药大学 | 2023-10-13 | — | — | CN | disclosed |