Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558061 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL25365319 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL25366809 | 0.88 | ALDH1A1 (0.38) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL30726179 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL26620710 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL30558043 | 0.82 | MAPT (0.41) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL25366055 | 0.82 | MAPT (0.41) | SMN1; SMN2MAPTTSHRKMT2ALMNA | |
| SCHEMBL25366832 | 0.81 | ALDH1A1 (0.41) | MAPTTSHRKMT2ALMNAMEN1 | |
| SCHEMBL30558073 | 0.81 | ALDH1A1 (0.41) | MAPTTSHRKMT2ALMNAMEN1 | |
| SCHEMBL25220710 | 0.76 | ALDH1A1 (0.45) | SMN1; SMN2MAPTTSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486454-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2025-01-08 | — | — | EP | disclosed |
| WO-2023156648-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-24 | — | — | WO | disclosed |