Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395221 | 1.00 | ALDH1A1 (0.64) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL25952873 | 0.93 | ALDH1A1 (0.56) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL15075888 | 0.93 | ALDH1A1 (0.56) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL16064422 | 0.91 | ALDH1A1 (0.54) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL21773689 | 0.91 | ALDH1A1 (0.53) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL3527609 | 0.89 | ALDH1A1 (0.50) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL30443727 | 0.88 | ALDH1A1 (0.64) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL12782425 | 0.87 | ALDH1A1 (0.48) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL16075222 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PKMABCB1ABCC1KDM4E | |
| SCHEMBL12788079 | 0.84 | ALDH1A1 (0.66) | ALDH1A1PKMKDM4ERAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |