Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784271 | 1.00 | PARP1 (0.51) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7816221 | 0.90 | PARP1 (0.49) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL2358023 | 0.73 | CYP1A2 (0.38) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL30577447 | 0.72 | PARP1 (0.56) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL1286636 | 0.72 | PARP1 (0.56) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11339431 | 0.72 | KDM4E (0.52) | PARP1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7816523 | 0.72 | CHEK1 (0.51) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7817340 | 0.72 | CHEK1 (0.41) | PARP1KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL7831092 | 0.72 | MEN1 (0.48) | PARP1MEN1KMT2ACHEK1GAA | |
| SCHEMBL21011371 | 0.71 | MAPT (0.37) | KDM4EALDH1A1LMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155826-A1 | MULTI-SUBSTITUTED TRICYCLIC FUSED HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 暨南大学 | 2023-08-24 | — | — | WO | disclosed |