Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577447 | 1.00 | PARP1 (0.56) | PARP1KDM4EALDH1A1HPGDPRNP | |
| SCHEMBL31272247 | 0.86 | PARP1 (0.56) | PARP1KDM4EALDH1A1HPGDPRNP | |
| SCHEMBL9204198 | 0.86 | PARP1 (0.56) | PARP1KDM4EALDH1A1HPGDPRNP | |
| SCHEMBL3472148 | 0.79 | CHEK1 (0.54) | PARP1KDM4EALDH1A1HPGDPRNP | |
| SCHEMBL4876781 | 0.77 | PARP1 (0.56) | PARP1CHEK1CDK4SRCCCND1 | |
| SCHEMBL30756753 | 0.74 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDPRNPNPSR1 | |
| SCHEMBL21052453 | 0.73 | PARP1 (0.71) | PARP1KDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL30231234 | 0.73 | PARP1 (0.71) | PARP1KDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL9784271 | 0.72 | PARP1 (0.51) | PARP1KDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL30558679 | 0.72 | PARP1 (0.51) | PARP1KDM4EALDH1A1HPGDCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173059-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-08 | — | — | US | claimed |
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | claimed |
| US-5010084-A | Antihistamines; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | claimed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | claimed |
| JP-3264585-A | — | — | None | — | — | JP | disclosed |
| US-20230173059-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-08 | — | — | US | disclosed |
| US-11661461-B2 | Phospho-Rab antibodies, assays and methods of use thereof | DENALI THERAPEUTICS INC. (US) | 2023-05-30 | — | — | US | disclosed |
| EP-4149550-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-03-22 | — | — | EP | disclosed |
| US-20220144865-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-05-12 | — | — | US | disclosed |
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-05-12 | — | — | US | disclosed |
| US-11274115-B2 | Imidazoquinoline derivatives and their use in therapy | GLAXOSMITHKLINE BIOLOGICAL SA (BE) | 2022-03-15 | — | — | US | disclosed |
| WO-2021231942-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2010139731-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |
| US-20100311714-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS | NOVARTIS AG (CH) | 2010-12-09 | — | — | US | disclosed |
| EP-0386722-B1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-07-26 | — | — | EP | disclosed |
| EP-0411394-B1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO KK (JP) | 1995-04-05 | — | — | EP | disclosed |
| JP-H03264585-A | IMIDAZOQUINOLONE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1991-11-25 | — | — | JP | disclosed |
| US-5010084-A | Antihistamines; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4994468-A | Bronchodilators, antiallergens | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0386722-A1 | Imidazoquinolone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144865-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | MAVS, IRF3, MYD88 | PARP1 1599/4885KDM4E 1661/4885ALDH1A1 3845/4885 |
| US-20100311714-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS | PRKCA, ABL1, MYLK2 | PARP1 2630/4885KDM4E 1210/4885ALDH1A1 2472/4885 |
| US-11274115-B2 | Imidazoquinoline derivatives and their use in therapy | MAVS, IRF3, MYD88 | PARP1 1599/4885KDM4E 1661/4885ALDH1A1 3845/4885 |
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | MAVS, IRF3, MYD88 | PARP1 1599/4885KDM4E 1661/4885ALDH1A1 3845/4885 |
| US-20230173059-A1 | TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF | TLR3, TLR9, TLR1 | PARP1 1037/4885KDM4E 3317/4885ALDH1A1 2917/4885 |
| US-11661461-B2 | Phospho-Rab antibodies, assays and methods of use thereof | RAB10, GTPBP10, RAB8A | PARP1 4047/4885KDM4E 1494/4885ALDH1A1 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.