Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715488 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL30498445 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL16094578 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL4716299 | 0.99 | MEN1 (0.41) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL4760645 | 0.99 | MEN1 (0.41) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL4711389 | 0.96 | ALDH1A1 (0.43) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL4715139 | 0.96 | ALDH1A1 (0.43) | ALDH1A1MAPTNR2F2NPSR1MAPK1 | |
| SCHEMBL14914394 | 0.89 | KMT2A (0.43) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30872620 | 0.89 | KMT2A (0.43) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL14914395 | 0.89 | KMT2A (0.43) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733184-B1 | PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-08-30 | — | — | EP | disclosed |