Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101135 | 0.79 | CACNA1F (0.49) | MEN1KMT2AGAACACNA1FCACNA1D | |
| SCHEMBL4795046 | 0.75 | GAA (0.41) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL10006896 | 0.69 | GRIA1 (0.46) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL6809086 | 0.68 | CACNA1F (0.33) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL84167 | 0.67 | GLA (0.35) | KMT2AGAACACNA1FCACNA1DCACNA1S | |
| SCHEMBL14676577 | 0.64 | HPGD (0.56) | MEN1KMT2ATSHRALDH1A1ATM | |
| SCHEMBL9585593 | 0.63 | ALDH1A1 (0.50) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL352276 | 0.63 | GAA (0.53) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL46517 | 0.62 | — | — | |
| SCHEMBL28077375 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116650483-A | Pirenpatanel pharmaceutical composition, pharmaceutical preparation containing same and preparation method | 山东达因海洋生物制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |