Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 14/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664315 | 1.00 | PRKDC (0.48) | PRKDCENPP1MAOBPIK3CDPIK3R1 | |
| SCHEMBL21664290 | 0.88 | ENPP1 (0.52) | PRKDCENPP1 | |
| SCHEMBL26553039 | 0.86 | PRKDC (0.49) | PRKDCKDM1A | |
| SCHEMBL21664291 | 0.85 | ENPP1 (0.50) | PRKDCENPP1 | |
| SCHEMBL30562895 | 0.85 | ENPP1 (0.50) | PRKDCENPP1 | |
| SCHEMBL21664420 | 0.84 | ENPP1 (0.49) | PRKDCENPP1 | |
| SCHEMBL30562896 | 0.84 | ENPP1 (0.49) | PRKDCENPP1 | |
| SCHEMBL21664327 | 0.84 | ENPP1 (0.49) | PRKDCENPP1 | |
| SCHEMBL21664418 | 0.84 | PRKDC (0.69) | PRKDC | |
| SCHEMBL21664260 | 0.84 | PRKDC (0.58) | PRKDCUSP2LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |